PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). It can dephosphorylate SV40 large T antigen and p53/TP53 and activates RAF1 by dephosphorylating it at ‘Ser-259'.
The Abbkine PP2AA Rabbit Polyclonal Antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen anddetects endogenous levels of PP2AA protein The antibody has been validaed in WB, ELISA and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-PP2AA Polyclonal Antibody at https://www.abbkine.com/product/pp2aa-polyclonal-antibody-abp59976/.
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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.