The protein encoded by GNA11 belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations. GNA11 (G Protein Subunit Alpha 11) is a Protein Coding gene. Diseases associated with GNA11 include Hypocalciuric Hypercalcemia, Type Ii and Hypocalcemia, Autosomal Dominant 2. Among its related pathways are Calcium signaling pathway and ADP signalling through P2Y purinoceptor 1.GNA11 (G Protein Subunit Alpha 11) is a Protein Coding gene. Diseases associated with GNA11 include Hypocalciuric Hypercalcemia, Type Ii and Hypocalcemia, Autosomal Dominant 2. Among its related pathways are Calcium signaling pathway and ADP signalling through P2Y purinoceptor 1.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000 ELISA 1:5000-20000.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.