POLR1A (RNA Polymerase I Subunit A) is a Protein Coding gene. Diseases associated with POLR1A include Acrofacial Dysostosis, Cincinnati Type and Acrofacial Dysostosis. Among its related pathways are Mismatch repair and Pyrimidine metabolism (KEGG). The protein encoded by this gene is the largest subunit of the RNA polymerase I complex. The encoded protein represents the catalytic subunit of the complex, which transcribes DNA into ribosomal RNA precursors. Defects in POLR1A are a cause of the Cincinnati type of acrofacial dysostosis.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000 ELISA 1:5000-20000.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.