Peroxisome proliferator-activated receptor deltais a member of the peroxisome proliferator-activated receptor (PPAR) family. It was first identified in Xenopus in 1993.PPAR-δ/β is the main target of a chemical substance named GW 501516. Using this ligand as a research ligand, It has been shown that agonism of PPAR-δ changes the body's fuel preference from glucose to lipids. PPAR-δ/β is highly expressed in colon, small intestine, liver and keratinocytes. In contrast, heart, spleen, skeletal muscle, lung, brain and thymus show low expression.Knockout mice lacking the ligand binding domain of PPAR-δ/β are viable. However these mice are smaller than the wild type both neo and postnatally. In addition, fat stores in the gonads of the mutants are smaller.

Rat Peroxisome proliferator-activated receptor beta (PPAR-B/PPARD) ELISA Kit employs a two-site sandwich ELISA to quantitate PPAR-B/PPARD in samples. An antibody specific for PPAR-B/PPARD has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPPAR-B/PPARD present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PPAR-B/PPARD is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PPAR-B/PPARD bound in the initial step. The color development is stopped and the intensity of the color is measured.

Rat Peroxisome proliferator-activated receptor beta (PPAR-B/PPARD) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/rat-peroxisome-proliferator-activated-receptor-beta-ppar-b-ppard-elisa-kit-kte100973/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.