On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.

Rat Anti-Activin A receptor antibody IgM (ACVR-Ab-IgM) ELISA Kit employs the competitive enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with an antibody specific to ACVR-Ab-IgM. Standards or samples are then added to the appropriate microtiter plate wells with a Horseradish Peroxidase (HRP)-conjugated ACVR-Ab-IgM and incubated. The competitive inhibition reaction is launched between with HRP labeled ACVR-Ab-IgM and unlabeled ACVR-Ab-IgM with the antibody. A substrate solution is added to the wells and the color develops in opposite to the amount of ACVR-Ab-IgM in the sample. The color development is stopped and the intensity of the color is measured.

Rat Anti-Activin A receptor antibody IgM (ACVR-Ab-IgM) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/rat-anti-activin-a-receptor-antibody-igm-acvr-ab-igm-elisa-kit-kte100920/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.