Noradrenaline is the neurotransmitter of the peripheral sympathetic nervous system, responsible for so-called adrenergic neurotransmission, at nerve endings in the heart, in smooth (involuntary) muscle, and in many glands. It is one of the catecholamines. Tyrosine, an amino acid present in body fluids, is taken up into the adrenergic nerve terminal where it is acted upon by an enzyme, tyrosine hydroxylase, to form DOPA; this is converted to dopamine and in turn to noradrenaline. The neurotransmitter is stored in small vesicles, awaiting release. Arrival of the impulse at the nerve terminal releases vesicles, freeing the noradrenaline to exert its effects. To terminate the action of the transmitter, some noradrenaline is oxidized to inactive material, but most is taken back up into the nerve terminal and stored for later use. There are two types of cell membrane receptors with which noradrenaline interacts, termed a and b, each group having several subtypes.

Rabbit Noradrenaline (NA) ELISA Kit employs a two-site sandwich ELISA to quantitate NA in samples. An antibody specific for NA has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyNA present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for NA is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of NA bound in the initial step. The color development is stopped and the intensity of the color is measured.

Rabbit Noradrenaline (NA) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.