May play a role in sperm morphology especially the sperm tail and consequently affect fertility. May also be involved in the general organization of cellular cytoskeleton.Cotransfection of PMF1 and NRF2 activated transcription from the polyamine-responsive element of the SSAT promoter in a reporter assay, and PMF1 was the rate-limiting component.Mutations that interrupted either of these regions altered the ability of the proteins to interact, and they lost their ability to regulate transcription of the SSAT gene.

Mouse Polyamine-modulated factor 1-binding protein 1 (PMFBP1) ELISA Kit employs a two-site sandwich ELISA to quantitate PMFBP1 in samples. An antibody specific for PMFBP1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPMFBP1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PMFBP1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PMFBP1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Mouse Polyamine-modulated factor 1-binding protein 1 (PMFBP1) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.