Xipamide acts on the kidneys to reduce sodium reabsorption in the distal convoluted tubule. This increases the osmolarity in the lumen, causing less water to be reabsorbed by the collecting ducts. Additionally, it increases the secretion of potassium in the distal tubule and collecting ducts. https://www.creative-peptides.com/product/xipamide-item-10-101-127-119.html

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