PharmaLegacy Laboratories (Shanghai) Co., Ltdlocated in Building 7, 388 Jialilue Road Zhangjiang High-Tech Park Pudong District Shanghai,Pudongxin District,City area,Shanghai,China,with elegant environment and convenience, market information delivered smoothly.PharmaLegacy is PharmaLegacy which is a specialized inBusiness services,Medical service,Medical insurance.

   

PharmaLegacyCarbon tetrachloride (CCl4)-induced hepatic fibrosis and cirrhosis in rodents is a well-established and widely accepted experimental model for the study of liver fibrosis and cirrhosis. In many aspects it mirrors the pattern of human disease associated with toxic damage. For example, the α-SMA expression, Stellate cell activation and key matrix components including collagen-1, MMPs and their inhibitors TIMPs have been indicated in the pathogenesis of this model. CCl4 induction elicits a reproducible and predictable fibrotic response in liver, making it a valuable basis for preclinical pharmacology studies of anti-fibrotic and anti-cirrhotic therapeutics and the pathophysiology study of liver fibrosis-cirrhosis-HCC changesis focused on Liver Fibrosis Model big brand, High quality Respiratory Disease Model, First rate service Respiratory Disease Model, Liver Fibrosis Model the quality and other projects. even though in the rapid development of the project ,PharmaLegacy always stressed the balance between external opportunities and internal management, attaches great importance to the core competitiveness of enterprises to cultivate and shape. Our company take the value of customer service as the core competitiveness of enterprises, adhering to the honesty and integrity , the pursuit of excellence, respect individual for the corporate spirit, and strive to provide customers with integrity and reliable Respiratory Disease Model.

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PharmaLegacy Laboratories is a leading speciality pharmacology Contract Research Organization located in Shanghai Zhangjiang High-Tech Park, China. PharmaLegacy is equipped with a world-class facility, working to international pharmaceutical industrial standards. PharmaLegacy provides preclinical in vivo pharmacology efficacy services as well a therapeutic antibody discovery service program. Our state-of-the-art platforms include:· Pioneering work using CD34+ humanized mice that carry a human immune system, to test biologics for immuno-oncology therapeutic efficacy· An NHP platform for therapeutic biologics testing in a variety of immune diseases · An advanced antibody discovery platform based on single B cell antibody sequencing · An internationally recognized Bone/Orthopaedics platform to test both hard tissue disease therapeutic candidates and medical devicesPharmaLegacy offers a full range of preclinical pharmacology services for evaluating pharmacological effects of drug candidates in the areas of inflammation/auto-Immune diseases, lung injury, liver/metabolic diseases and oncology. Our NHP platform and CD34+ humanized mice models have helped dozens of clients with IND filings