Creative Animodel offers a complete range of GLP-compliant ICH S7A core battery tests to determine the potential undesirable pharmacodynamic effects of a compound.

Safety pharmacology is the study of the potential undesirable pharmacodynamic effects of a substance in relation to dosage within the substance's therapeutic range and above. It provides valuable insight into a drug's adverse effects, preview what may be observed clinically and provide essential information about likely side effects on the major physiological systems of the body. Creative Animodel offers a complete range of GLP-compliant ICH S7A core battery tests to determine the potential undesirable pharmacodynamic effects of a compound.

 

http://www.creative-animodel.com/Toxicology/Infusion-models-and-studies.html

Creative Animodel has collected more than 80 cases of human tumors. At present, 30 cases are growing as subcutaneous xenografts in nude mice, and others were retained as nitrogen frozen samples. Tumors types comprise: stomach, lung, liver, pancreas, kidney, bladder, skin, breast, brain, colon, prostate, sarcomas (bone), uterus, ovary and hematological models. Also, we have a full range of human tumor cell lines that have been validated in our in vivo efficacy studies or reported in literature. According to the requirements from clients and our experience, Creative Animodel can offer subcutaneous, orthotopic, metastatic, transgenic and chemo-induced models using these tumor samples and cell lines.