Creative Animodel conducts typical PK study which involves administering a fixed amount of the drug (the dose) to the subject (various animals) and at various times post dose, samples of an easily accessible tissue (usually blood/plasma) are drawn and collected for analysis of the drug and its metabolite concentrations.http://www.creative-animodel.com/PK-PD/Drug-Metabolism-and-Pharmacokinetic-Services.html

Creative Animodel has collected more than 80 cases of human tumors. At present, 30 cases are growing as subcutaneous xenografts in nude mice, and others were retained as nitrogen frozen samples. Tumors types comprise: stomach, lung, liver, pancreas, kidney, bladder, skin, breast, brain, colon, prostate, sarcomas (bone), uterus, ovary and hematological models. Also, we have a full range of human tumor cell lines that have been validated in our in vivo efficacy studies or reported in literature. According to the requirements from clients and our experience, Creative Animodel can offer subcutaneous, orthotopic, metastatic, transgenic and chemo-induced models using these tumor samples and cell lines.