Preparative Separation and Purification
Sepax has developed proprietary process for separation and purification of complex pharmaceutical mixtures, natural products and biological samples with high speed and in highly economical way. Sepax has accumulated a wide range of expertise and skills in separating and purifying a mixture of a few of compounds to a natural product of more than 500 compounds effectively. The separation and purification covers small molecules to peptides to proteins, such as antibodies.
Uniqueness
- Sepax manufactures more than 200 different separation media, covering silica and polymer materials with particle selection from 1 to 100 µm and pore size selection from 60 to 2000 Å. The chemistry includes reversed phases, normal phases, HILIC, ion-exchange, size exclusion, SFC, affinity and custom-synthesized phases.
- Sepax manufactures preparative separation columns covering flash chromatography to HPLC. The column dimensions are from regular 2 and 3 cm ID to larger ones for process separation.
- Sepax has accumulated a variety of proprietary expertise, techniques, and skills for fast and economical separation and purification processes. Sepax purified more than 35,000 compounds from natural products in 2007.
- Sepax has strong expertise and experts on mass spectrometry analysis to further test the purified compounds.
Facilities for Separation and Purification
- More than 20 HPLC equipments
- 3 Mass Spectrometers
- Bulk separation media and columns manufactured in house
- Lyophilization equipments
- 10,000 ft² lab space and 50,000 ft² lab space is under construction
Separation and Purification Areas
- Pharmaceutical and neutraceuticals
- Natural products and traditional Chinese medicine
- Peptides
- Proteins, e.g. antibodies and enzymes
- Oligonucleotides and DNA
- Nanomaterials, e.g. nanoparticles, carbon nanotubes
- Cell lysates
Methods
- Extraction
- Flash Chromatography
- Thin layer chromatography
- HPLC separation
- Preparative LC separation
Characterization & Identification
- LC chromatography
- UV-vis
- LC/MS
- NMR
Example - Natural Product Separation
bio-equip.cn
Profile
Sepax Technologies, Inc., a privately held company, was founded in Delaware, USA in November 2002. It develops and manufactures HPLC consumables, bulk media, and equipment in liquid chromatography for chemical and biological separations. It is a fast growing technology company and owns patents, proprietary technologies and know-how. Sepax has emerged as a leader in the biological separation industry in the global market.
Business strategies
Sepax Technologies, Inc. develops innovative HPLC consumables, bulk media, and instruments to solve separation challenges in the global market. We provide solution-based products by closely working with our customer scientists in pharmaceuticals, biopharmaceuticals, research institutes and government labs. Our strong technical team develops various methods with our customers to analyze complex biological molecules. As a leader in the biological separation industry, we constantly develop the best bio-separation technologies and products for our global customers. We have reached a competitive position globally in fast growing regions.
Vision Statement
To become a technology leader in the biological separation industry in the global market and provide solution based products and services for our customers.
Operation
Sepax Technologies, Inc.
Our company headquarter in Delaware is located in Delaware Technology Park with facilities of 15,000 ft2 dedicated to the development of separation resin technologies and instrumentation, production of HPLC resins, columns and CE consumables. It is also the marketing and sales center for our US and global markets.
Sales
Domestic
Audrey Fisher
Field Sales Account Manager
(Northern CA areas, UT, CO, OR)
Direct Phone: 925-324-5223
Email: afisher@sepax-tech.com
Kathleen Falls
West Coast Regional Manager
(All other CA areas, WA, TX, AZ, NM, MI)
Direct Phone: 323-228-0004
Email: kfalls@sepax-tech.com
Michael Hunnewell
Field Sales Account Manager
(MA, RI, NH, CT, NY)
Direct Phone: 302-650-3955
Email: mhunnewell@sepax-tech.com
Colleen Callahan
Midwest Account Manager
(WI, IL, IN, OH, MO)
Direct Phone: 302-366-1101, ext 106
Cell Phone: 302-339-8747
Email: ccallahan@sepax-tech.com
All other areas, please contact
Helen Gu
Vice President, Sales
Direct phone: 302-650-3909
Email: hgu@sepax-tech.com
International
Tingting Wu
Executive Account Manager/Marketing
Phone: 302-366-1101, ext 115
Email: twu@sepax-tech.com
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