AccuSift provides high-performance antibody pairings for sulfonamides (SAs), delivering exceptional batch-to-batch consistency and optimized for IVD kit development (Lateral Flow, Chemiluminescence, ELISA, POCT). These pairings offer high affinity and specificity to facilitate rapid detection.

Sulfonamides are folate synthesis inhibitors, consistently used due to their low cost and efficacy against pathogens causing urinary tract infections, trachoma, and other diseases. Their structure is similar to para-aminobenzoic acid (PABA), allowing them to competitively inhibit bacterial dihydropteroate synthase. This action prevents the synthesis of bacterial dihydrofolic acid, thereby inhibiting bacterial growth and reproduction. Sulfonamides are broad-spectrum antibacterial agents effective against both Gram-positive and Gram-negative bacteria, selectively inhibiting Streptococcus pyogenes, Streptococcus pneumoniae, Haemophilus influenzae, Escherichia coli, Proteus mirabilis, Chlamydia trachomatis, Chlamydia lymphogranuloma venereum, as well as Actinomyces, Pneumocystis, and Nocardia.

Most systemically administered sulfonamides are readily absorbed orally and distribute widely into body tissues and fluids. They penetrate various extracellular fluids (pleural, peritoneal, synovial, aqueous humor), saliva, sweat, urine, and bile. They cross the blood-brain barrier, enter breast milk, and pass through the placenta.

Product SE205:

•Sensitivity: ELISA IC50: 0.7 ppb; Colloidal Gold Visual Cut-off: 2 ppb

•Cross-Reactivity (IC50, ppb):

1.Phthalylsulfathiazole (PST): 0.25

2.Sulfaquinoxaline (SQX): 0.25

3.Sulfamethoxydiazine (SMD): 0.25

4.Sulfadimethoxine (SDM): 0.45

5.Sulfabenzamide (SBA): 0.45

6.Sulfamoxole (SMO): 0.45

7.Sulfadimidine/Sulfamethazine (SM2): 0.65

8.Sulfisomidine (SM'): 0.65

9.Sulfanitran (SN): 0.65

10.Sulfisoxazole (SIZ): 0.65

11.Sulfamonomethoxine (SMM): 1.0

12.Sulfaclozine (SPZ): 1.0

13.Sulfadiazine (SD): 1.45

14.Sulfadoxine (SDM'): 1.45

15.Sulfachloropyridazine (SCP): 1.45

16.Sulfamethoxypyridazine (SMPZ): 1.45

17.Sulfacetamide (SA): 1.45

18.Sulfalene/Sulfamethoxypyrazine (SMP2): 1.45

19.Sulfamerazine (SMZ): 2.0

20.Sulfanilamide (SN): 2.0

21.Sulfaphenazole (SPP): 2.0

22.Sulfasalazine (SASP/SSZ): 2.0

23.Sulfamethoxazole (SMZ): 3.0

24.Sulfapyridine (SP): 5.0

25.Sulfamethizole (SMZ): 6.0

26.Sulfathiazole (ST): 14.0

 

https://en.accusift.com/index.php?c=show&id=3452

 

Shenzhen AccuSift Biotechnology Co., Ltd. (referred to as AccuSift) was established in January 2014. It is a technology-oriented enterprise specializing in the preparation of antigens and antibodies for IVD raw materials and food safety raw materials, as well as the development and application of biotechnology. The company has an advanced and complete production platform for single and polyclonal antibodies and has prepared a variety of small molecule hapten related to IVD raw materials, pesticides and veterinary drugs, antibiotics, mycotoxins, hormones, heavy metals, pigments, etc., and high-quality monoclonal antibodies. The company provides comprehensive antibody services, antigen design, synthesis, antibody preparation and labeling, and immunological experiments for domestic and foreign users. The company's antibody research and development department has high-quality talents, strong research and development capabilities and a quality assurance system, providing high-precision and high-stability product solutions for clinical diagnosis and food safety detection.

AccuSift adheres to the business philosophy of "integrity, innovation and progress", with the mission of "focusing on the source of precision and safeguarding the beauty of health", providing strong support for researchers in the fields of clinical diagnosis and food safety.