HB-EGF Protein, Rat,specification,price,image-Bio-Equip in China

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Product Specification

Species	Rat
Accession	Q06175
Amino Acid Sequence	Asp63-Leu148
Expression System	E.coli
Molecular Weight	10 kDa (Reducing)
Purity	>95% by SDS-PAGE.
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, pH7.4
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	·12 months from date of receipt, lyophilized powder stored at -20 to -80℃. ·3 months, -20 to -80℃ under sterile conditions after reconstitution. ·1 week, 2 to 8℃ under sterile conditions after reconstitution. ·Please avoid repeated freeze-thaw cycles.
Reference	Diabetes. 2020 Mar;69(3):369-380. Gastroenterology. 2003 Apr;124(4):1020-36.

Background

Heparin-Binding Epidermal Growth Factor-like Growth Factor (HB-EGF) is a multifunctional growth factor that plays a crucial role in various cellular processes, including proliferation, differentiation, and tissue repair. In rats, HB-EGF has been extensively studied for its role in pancreatic beta-cell proliferation and glucose homeostasis.
HB-EGF has been studied extensively in rat models of diabetes to understand its role in beta-cell regeneration and proliferation. For instance, HB-EGF has been shown to promote beta-cell proliferation in rats with partial pancreatectomy. This suggests that HB-EGF could be a potential therapeutic target for enhancing beta-cell mass and improving glucose homeostasis in diabetes.