DLK1/FA1 His Tag Protein, Cynomolgus,specification,price,image-Bio-Equip in China

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Product Specification

Species	Cynomolgus
Synonyms	Protein delta homolog 1, Pg2, Fetal antigen 1
Accession	A0A2K5TMQ6-1
Amino Acid Sequence	Ala24-Cys306 with His Tag at the C-terminus
Expression System	HEK293
Molecular Weight	33-45kDa (Reducing)
Purity	＞95% by SDS-PAGE & SEC-HPLC
Conjugation	Unconjugated
Tag	His Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, PH7.4, 5% trehalose
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	Sheng J, Wu D, Shang J, Fu X, Gao H, Rong J, Wang J, Hu J, Qi X. Usp11 maintained the survival of marginal zone B cells under ionizing radiation by deubiquitinating DLL1 and JAG2. Cell Death Dis. 2025 Feb 4;16(1):67.

Background

DLK-1, also known as preadipocyte factor 1 (Pref-1), is a transmembrane-secreted protein containing an epidermal growth factor (EGF)-like repeat sequence. It is expressed on the cell surface in various cancers, including hepatocellular carcinoma, and may serve as a potential target for monoclonal antibody therapy. DLK-1 regulates the growth of pioneer axons by modulating Wnt signaling. While primarily expressed as a transmembrane protein, a soluble form generated by ADAM17-mediated cleavage is active in inhibiting adipogenesis, the process by which pre-adipocytes differentiate into adipocytes.