Glypican 1/GPC1(S486A, S488A, S490A) His Tag Protein, Human,specification,price,image-Bio-Equip in China

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Product Specification

Species	Human
Synonyms	FLJ38078; Glypican 1; glypican proteoglycan 1; glypican; glypican-1; GPC1
Accession	P35052-1
Amino Acid Sequence	Asp24-Ser530 with His Tag at C-Terminus
Expression System	HEK293
Molecular Weight	55-72kDa (Reducing)
Purity	> 95% by SDS-PAGE & SEC-HPLC
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	His Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, PH7.4,5% trehalose
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1.Song, H.H. and J. Filmus (2002) Biochim. Biophys. Acta 1573:241. 2.Fransson, L-A. et al. (2004) Cell. Mol. Life Sci. 61:1016. 3.De Cat, B. and G. David (2001) Semin. Cell Dev. Biol. 12:117. 4.Lamoureux, F. et al. (2007) BioEssays 29:758.

Background

Glypicans, a small multigene family of glycosylphosphatidylinositol (GPI)-linked proteoglycans, play a pivotal role in growth factor signaling. GPC-1, a member of the glypican family, is expressed in various cell types including neurons, smooth and skeletal muscle cells, keratinocytes, osteoblasts, Schwann cells, immature dendritic cells, tumor cells, and tumor-associated vascular endothelial cells. The glypican-related integral membrane proteoglycan family (GRIPS) consists of core proteins anchored to the plasma membrane via a glycosyl phosphatidylinositol linkage. These proteins are implicated in the regulation of cell division and growth control.