Product Specification| Synonyms | Ebola virus EBOV (subtype Sudan, strain Gulu), GP, Envelope glycoprotein, GP (1,2) | | Accession | Q7T9D9 | | Amino Acid Sequence | Met33-Asp320 with Human IgG1 Fc Tag at the C-terminus | | Expression System | HEK293 | | Molecular Weight | 73-95kDa (Reducing) | | Purity | ＞95% by SDS-PAGE & ＞90% by SEC-HPLC | | Conjugation | Unconjugated | | Tag | Human IgG1 Fc | | Physical Appearance | Lyophilized Powder | | Storage Buffer | PBS, PH7.4, 5% trehalose | | Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. | | Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles. | | Reference | 1. Wang, Han et al.Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1.Cell.Volume 164;Issue 1:258 - 268 |
BackgroundEbola virus glycoprotein (GP1), acting as a receptor-binding subunit, is crucial for the virus entry process. In the late stages of infection, GP1 downregulates key host cell surface molecules, including integrins such as ITGA1-6, which can disrupt cell adhesion and potentially lead to compromised vascular integrity. bio-equip.cn AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
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