TPBG/5T4 His Tag Protein, Human,specification,price,image-Bio-Equip in China

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Product Specification

Species	Human
Synonyms	TPBG,5T4, M6P1,5T4AG, WAIF1 ,5T4 oncofetal trophoblast glycoprotein
Accession	Q13641
Amino Acid Sequence	Ser32-Ser355 with His tag at the C-Terminus
Expression System	HEK293
Molecular Weight	50-72kDa (Reducing)
Purity	＞95% by SDS-PAGE & SEC-HPLC
Conjugation	Unconjugated
Tag	His Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, PH7.4, 5% trehalose
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	Li F, Wang Y, Cao J, Chen Q, Gao Y, Li R, Yuan L. Integrated analysis of genes shared between type 2 diabetes mellitus and osteoporosis. Front Pharmacol. 2024 Jun 20; 15:1388205.

Background

Trophoblast glycoprotein (TPBG), also known as 5T4, is a therapeutic target for several anticancer agents in clinical development. This is primarily due to its high expression in tumors and low expression in normal adult tissues. The TPBG gene encodes a leucine-rich transmembrane glycoprotein that may play a role in cell adhesion. TPBG is expressed by all types of trophoblasts as early as the ninth week of development.