NCAM-1/CD56 Fc Chimera Protein, Human,specification,price,image-Bio-Equip in China

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Product Specification

Species	Human
Synonyms	CD56, MSK39, NCAM1, N-CAM-1
Accession	P13591-2
Amino Acid Sequence	Leu20-Gly718 with Human IgG1 Fc at C-Terminus
Expression System	HEK293
Molecular Weight	110-130kDa (Reducing)
Purity	＞95% by SDS-PAGE
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	Human IgG1 Fc
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, PH7.4
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1、Guven A. et al. (2021) Development and validation of an immunoassay for quantification of NCAM-1 in human plasma. Journal of Pharmaceutical and Biomedical Analysis. 197: 113981.

Background

Neural Cell Adhesion Molecule 1 (NCAM-1), a multifunctional member of the immunoglobulin superfamily, is expressed on the surfaces of neurons, glial cells, skeletal muscle, and natural killer cells. NCAM-1 plays a role in cell-cell adhesion and is crucial for the development of the nervous system. It is also involved in the expansion of T cells and dendritic cells, which are key players in immune surveillance.