TREM-1/CD354 Fc Chimera Protein, Mouse,specification,price,image-Bio-Equip in China

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Product Specification

Species	Mouse
Synonyms	CD354 antigen; CD354; TREM1; TREM-1; TREM-1Triggering receptor expressed on monocytes 1; triggering receptor expressed on myeloid cells 1; triggering-receptor TREM1
Accession	Q9JKE2
Amino Acid Sequence	Ala21-Ser202 with Human IgG1 Fc at C-Terminus
Expression System	HEK293
Molecular Weight	55-72kDa (Reducing)
Purity	＞95% by SDS-PAGE &＞95% by SEC-HPLC
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	Huamn IgG1 Fc
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, PH7.4, 5% trehalose
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1.Bouchon A, Dietrich J, Colonna M. Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes. J Immunol. 2000;164:4991–5.

Background

The TREM-1 protein, a pivotal cell surface receptor, plays a crucial role in amplifying inflammatory responses within both the innate and adaptive immune systems. Activation of TREM-1 by ligands such as PGLYRP1, HMGB1, or HSP70 triggers multimerization of the receptor and subsequent complex formation with the signaling adaptors TYROBP (also known as DAP12).