CD229/SLAMF3 His Tag Protein, Mouse,specification,price,image-Bio-Equip in China

Product Detail
Company Profile

Product Specification

Species	Mouse
Synonyms	SLAMF3, Ly9, Ly-9
Accession	Q4VBG4
Amino Acid Sequence	Lys48-Phe454 with His Tag at C-Terminus
Expression System	HEK293
Molecular Weight	70-80kDa (Reducing)
Purity	＞95% by SDS-PAGE & ＞90% by SEC-HPLC
Conjugation	Unconjugated
Tag	His Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, PH7.4, 5% trehalose
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	Somuncular E, Su TY, Dumral Ö, Johansson AS, Luc S. Combination of CD49b and CD229 Reveals a Subset of Multipotent Progenitors With Short-Term Activity Within the Hematopoietic Stem Cell Compartment. Stem Cells Transl Med. 2023 Nov 3;12(11):720-726.

Background

CD229, also known as Ly9 or SLAMF3, is a 120 kDa type I transmembrane glycoprotein belonging to the SLAM subgroup within the CD2 family. This protein is prominently expressed on T and B cells, thymocytes, and to a lesser extent on NK cells. The N-terminal Ig-like domain of CD229 facilitates homophilic binding between CD229 molecules.CD229/SLAMF3 serves as an autoligand receptor within the SLAM family, playing a crucial role in the regulation of immune cell activation and differentiation. It achieves this through homotypic or heterotypic interactions, which are essential for modulating immune responses.