IL-10 Protein, Canine,specification,price,image-Bio-Equip in China

Product Detail
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Product Specification

Species	Canine
Synonyms	Interleukin-10; IL-10; Cytokine synthesis inhibitory factor (CSIF);
Accession	P48411
Amino Acid Sequence	Ser20-ILe181
Expression System	E.coli
Molecular Weight	20 kDa (Reducing)
Purity	>95% by SDS-PAGE.
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, pH7.4
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	J Interferon Cytokine Res. 1995 Dec;15(12):1103-9.

Background

Interleukin-10 (IL-10) is a key immunoregulatory cytokine that plays a crucial role in modulating immune responses and maintaining immune homeostasis. In dogs, IL-10 is produced by various immune cells, including monocytes, macrophages, and T cells, and functions as an anti-inflammatory cytokine by inhibiting the production of pro-inflammatory mediators and suppressing immune cell activation. IL-10 is involved in regulating immune tolerance, controlling excessive inflammation, and promoting tissue repair in dogs. Studies on canine IL-10 have focused on its role in infectious diseases, autoimmune conditions, and cancer, highlighting its importance in canine health and disease.