FGF-5 Protein, Human,specification,price,image-Bio-Equip in China

Product Detail
Company Profile

Product Specification

Species	Human
Synonyms	Fibroblast growth factor 5; FGF-5; Heparin-binding growth factor 5 (HBGF-5); Smag-82;
Amino Acid Sequence	His21-Gly268
Expression System	E.coli
Molecular Weight	30 kDa (Reducing)
Purity	>95% by SDS-PAGE.
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	20mM Tris, 500mM NaCl, 1mM DTT, pH8.0
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19679-88.

Background

Fibroblast Growth Factor 5 (FGF-5) is a member of the fibroblast growth factor (FGF) family, which plays a crucial role in various cellular processes, including cell proliferation, differentiation, and survival. FGF-5 is primarily known for its involvement in regulating hair growth and cycling. It is expressed in the hair follicles and acts as a negative regulator of hair follicle growth. FGF-5 signaling is essential for the transition between different phases of the hair growth cycle, including the growth phase (anagen), regression phase (catagen), and resting phase (telogen). Dysregulation of FGF-5 expression or activity has been linked to hair loss disorders, such as alopecia, highlighting its importance in hair follicle biology.