IL-11 Protein, Human,specification,price,image-Bio-Equip in China

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Product Specification

Species	Human
Synonyms	Interleukin-11; IL-11; Adipogenesis inhibitory factor; Oprelvekin;
Accession	P20809
Amino Acid Sequence	Gly23-Leu199
Expression System	E.coli
Molecular Weight	22 kDa (Reducing)
Purity	>95% by SDS-PAGE and HPLC.
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	20mM Tris, 200mM NaCl, pH9.0
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	J Leukoc Biol. 2010 Dec;88(6):1109-17. Epub 2010 Jul 7.

Background

Interleukin-11 (IL-11) is a cytokine that belongs to the interleukin-6 (IL-6) family of cytokines. IL-11 is produced by various cell types, including stromal cells, fibroblasts, and immune cells, and plays a critical role in regulating hematopoiesis, bone metabolism, and gastrointestinal mucosal integrity. IL-11 exerts its effects through binding to the IL-11 receptor complex, leading to the activation of signaling pathways involved in cell proliferation, differentiation, and survival. IL-11 is known for its anti-inflammatory and tissue-protective properties, making it a potential therapeutic target for various inflammatory and tissue injury-related conditions.