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BD-2 Protein, Human
BD-2 Protein, Human
Origin of place Singapore
Model UA040322-10μg
Supplier ANT BIO PTE.LTD.
Price 124
Hits 9
Updated 9/1/2025
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Product Specification


SpeciesHuman
SynonymsDefensin beta 4A; Beta-defensin 2; Defensin, beta 2; Skin-antimicrobial peptide 1 (SAP1);
AccessionO15263
Amino Acid Sequence

Gly24-Pro64

Expression SystemE.coli
Molecular Weight

5 kDa (Reducing)

Purity>95% by SDS-PAGE and HPLC.
Endotoxin<0.1EU/μg
ConjugationUnconjugated
TagNo Tag
Physical AppearanceLyophilized Powder
Storage BufferPBS, pH7.4
Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

Science. 2002 Nov 1;298(5595):1025-9.

Background

Beta-defensin 2 is a key component of the innate immune system, known for its antimicrobial properties and immunomodulatory functions. It is produced by various epithelial cells in response to microbial infections and plays a crucial role in host defense against pathogens. Beta-defensin 2 exhibits potent antimicrobial activity against a wide range of microorganisms, including bacteria, fungi, and viruses, by disrupting their cell membranes. In addition to its direct antimicrobial effects, beta-defensin 2 also functions as a chemoattractant for immune cells, such as neutrophils, monocytes, and dendritic cells, promoting their recruitment to sites of infection. Furthermore, beta-defensin 2 can modulate inflammatory responses by regulating cytokine production and promoting wound healing.

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