LIGHT Protein, Mouse,specification,price,image-Bio-Equip in China

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Product Specification

Species	Mouse
Synonyms	Tumor necrosis factor ligand superfamily member 14; TNFSF14; CD258;
Accession	Q9QYH9
Amino Acid Sequence	Asp72-Val239
Expression System	E.coli
Molecular Weight	18 kDa (Reducing)
Purity	>95% by SDS-PAGE and HPLC.
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, pH7.4
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	J Immunol. 2001 Dec 1;167(11):6330-7.

Background

TNFSF14, also known as tumor necrosis factor ligand superfamily member 14 or LIGHT (homologous to lymphotoxins, exhibits inducible expression, and competes with HSV glycoprotein D for HVEM, a receptor expressed by T lymphocytes), is a cytokine belonging to the tumor necrosis factor (TNF) superfamily. It is expressed on the surface of activated T cells, natural killer cells, and immature dendritic cells. TNFSF14 plays a crucial role in regulating immune responses, inflammation, and lymphoid organ development. It can bind to two receptors, herpes virus entry mediator (HVEM) and lymphotoxin beta receptor (LTβR), and modulate various immune functions, including T cell activation, cytokine production, and lymphoid tissue organization.