Product SpecificationSpecies | Mouse | Synonyms | Beta-defensin 2; BD-2; mBD-2; Defensin, beta 2; | Accession | P82020 | Amino Acid Sequence | Ala21-Lys71 | Expression System | E.coli | Molecular Weight | 5 kDa (Reducing) | Purity | >95% by SDS-PAGE. | Endotoxin | <0.1EU/μg | Conjugation | Unconjugated | Tag | No Tag | Physical Appearance | Lyophilized Powder | Storage Buffer | PBS, pH7.4 | Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. | Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
| Reference | Science. 2002 Nov 1;298(5595):1025-9. |
BackgroundBeta-defensin 2 is a key component of the innate immune system, known for its antimicrobial properties and immunomodulatory functions. It is produced by various epithelial cells in response to microbial infections and plays a crucial role in host defense against pathogens. Beta-defensin 2 exhibits potent antimicrobial activity against a wide range of microorganisms, including bacteria, fungi, and viruses, by disrupting their cell membranes. In addition to its direct antimicrobial effects, beta-defensin 2 also functions as a chemoattractant for immune cells, such as neutrophils, monocytes, and dendritic cells, promoting their recruitment to sites of infection. Furthermore, beta-defensin 2 can modulate inflammatory responses by regulating cytokine production and promoting wound healing. bio-equip.cn
AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
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