BD-5 Protein, Human,specification,price,image-Bio-Equip in China

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Product Specification

Species	Human
Synonyms	Beta-defensin 105; Beta-defensin 5 (BD-5; DEFB-5); Defensin, beta 105;
Accession	Q8NG35
Amino Acid Sequence	Gly28-Ile78
Expression System	E.coli
Molecular Weight	5 kDa (Reducing)
Purity	>95% by SDS-PAGE.
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	20mM PB, 250mM NaCl, pH6.5
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	Nature. 2003 Apr 3;422(6931):522-6.

Background

Beta-defensin 5 is a member of the defensin family of antimicrobial peptides that play a crucial role in the innate immune system's defense against pathogens. It is primarily expressed in the gastrointestinal tract, where it contributes to maintaining the mucosal barrier integrity and protecting against microbial invasion. Beta-defensin 5 exhibits potent antimicrobial activity against a wide range of pathogens, including bacteria, fungi, and viruses, by disrupting their cell membranes. In addition to its direct antimicrobial effects, beta-defensin 5 also plays a role in modulating immune responses, promoting wound healing, and maintaining the balance of the gut microbiota.