CCL17/TARC Protein, Human,specification,price,image-Bio-Equip in China

Product Detail
Company Profile

Product Specification

Species	Human
Synonyms	C-C motif chemokine 17; CC chemokine TARC; Small-inducible cytokine A17; Thymus and activation-regulated chemokine;
Accession	Q92583
Amino Acid Sequence	Ala24-Ser94
Expression System	E.coli
Molecular Weight	10 kDa (Reducing)
Purity	>95% by SDS-PAGE and HPLC.
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	20mM PB, 500mM NaCl, pH7.4
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	Int Immunol. 1999 Jan;11(1):81-8.

Background

CCL17, also known as thymus and activation-regulated chemokine (TARC), is a small cytokine belonging to the CC chemokine family. It is produced by various cell types, including dendritic cells, macrophages, and endothelial cells, and plays a crucial role in regulating immune cell migration and activation. CCL17/TARC is involved in the recruitment of T cells, particularly T helper type 2 (Th2) cells, to sites of inflammation and is implicated in the pathogenesis of allergic and inflammatory diseases, such as atopic dermatitis and asthma. CCL17/TARC binds to its receptor CCR4 and mediates chemotaxis of CCR4-expressing cells, contributing to the orchestration of immune responses.