GM-CSF Protein, Rat,specification,price,image-Bio-Equip in China

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Product Specification

Species	Rat
Synonyms	Granulocyte-macrophage colony-stimulating factor, Colony-stimulating factor (CSF), GM-CSF
Accession	P48750
Amino Acid Sequence	Ala18-Lys144
Expression System	E.coli
Molecular Weight	14.5 kDa (Reducing)
Purity	>95% by SDS-PAGE and HPLC.
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	20mM Tris,100mM NaCl, pH8.0
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1.Cell Mol Immunol. 2021 Aug;18(8):2057-2058. Epub 2021 Jul 19. 2.Biomaterials. 2021 May: 272:120786. Epub 2021 Mar 31.

Background

Granulocyte-macrophage colony-stimulating factor (GM-CSF), which belongs to the colony-stimulating factor (CSF) superfamily and was originally identified as a hemopoietic growth factor, is mainly produced by lymphocytes and innate lymphoid cells. During inflammation, GM-CSF is principally produced by T helper (Th) cells and acts as a communication conduit between myeloid cells and tissue-invading lymphocytes. GM-CSF increased Treg numbers and its immunoregulatory activities that led directly to dopaminergic neuronal protection in the substantia nigra and striatum