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FGF-10 Protein, Rat
FGF-10 Protein, Rat
Origin of place Singapore
Model UA040262-10μg
Supplier ANT BIO PTE.LTD.
Price 140
Hits 5
Updated 8/27/2025
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Product Specification


SpeciesRat
SynonymsFGF-10, Fibroblast Growth Factor-10, FGFA, Keratinocyte growth factor-2, KGF2
AccessionP70492
Amino Acid SequenceGln37-Ser215
Expression SystemE.coli
Molecular Weight

23kDa (Reducing)

Purity>95% by SDS-PAGE&HPLC
Endotoxin<0.1EU/μg
ConjugationUnconjugated
TagNo Tag
Physical AppearanceLyophilized Powder
Storage Buffer20mM Tris, 200mM NaCl, pH8.0
Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1、Hubert F. et al. (2022) FGF10 promotes cardiac repair through a dual cellular mechanism increasing cardiomyocyte renewal and inhibiting fibrosis. Cardiovasc Res. 118(12): 2625-2637.
2、Sun W. et al. (2019) Cytokine fibroblast growth factor 10 (FGF10) polymorphisms are associated with risk of myopia in young children. J Cell Biochem. 120(9): 15241-15247.

Background

Fibroblast growth factor 10 (FGF-10), a secreted heparin-binding protein, is a member of the fibroblast growth factor (FGF) family and is also known as Keratinocyte Growth Factor-2 (KGF-2). FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies revealed that genetic variants of FGF10 were associated with extreme myopia in adults.

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