IL-1RAcP/IL-1R3 His Tag Protein, Cynomolgus/Rhesus macaque,specification,price,image-Bio-Equip in China

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Product Specification

Species	Cynomolgus
Synonyms	IL1RAP, IL-1RAcP, C3orf13, IL1R3
Accession	P59822-1
Amino Acid Sequence	Ser21-Glu359, with C-terminal His
Expression System	HEK293
Molecular Weight	55-65kDa (Reducing)
Purity	＞95% by SDS-PAGE & ＞95% by SEC-HPLC
Endotoxin	<0.1EU/μg
Tag	His Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, 5% trehalose, PH7.4
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1. Eggestøl HØ, Lunde HS, Knutsen TM, Haugland GT. Interleukin-1 Ligands and Receptors in Lumpfish (Cyclopterus lumpus L.): Molecular Characterization, Phylogeny, Gene Expression, and Transcriptome Analyses. Front Immunol. 2020 Apr 2; 11:502.

Background

Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. Interleukin 1 induces the synthesis of the acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein.