EGF Protein, Rat,specification,price,image-Bio-Equip in China

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Product Specification

Species	Rat
Synonyms	Pro-epidermal growth factor, Epidermal growth factor, EGF
Accession	P07522
Amino Acid Sequence	N974-R1026
Expression System	E.coli
Molecular Weight	6kDa
Purity	＞95% by SDS-PAGE
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	20mM PB, 100mM NaCl, pH6.0
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1.Int J Pancreatol. 1992 Aug;12(1):23-9. 2.Cell Biol Int. 1995 May;19(5):413-30. 3.J Cell Biochem. 1986;31(2):135-52.

Background

Epidermal growth factor (EGF) has been localized in human salivary and Brunner's glands and found to stimulate the proliferation of gastrointestinal and pancreatic tissues in animals, is a single polypeptide of 53 amino acid residues which is involved in the regulation of cell proliferation. EGF exerts its effects in the target cells by binding to the plasma membrane located EGF receptor. And The EGF receptor is a transmembrane protein tyrosine kinase. EGF is also a peptide which effects the growth and/or differentiated functions of many cell types. Several pieces of evidence indicate that EGF and its receptor may play a role in carcinogenesis.