Product Specification| Species | Human | | Synonyms | CD171,L1CAM | | Accession | P32004 | | Amino Acid Sequence | Ile20-Glu1120, with C-terminal His | | Expression System | HEK293 | | Molecular Weight | 150-180kDa (Reducing) | | Purity | ＞95% by SDS-PAGE | | Endotoxin | <0.1EU/μg | | Conjugation | Unconjugated | | Tag | His Tag | | Physical Appearance | Lyophilized Powder | | Storage Buffer | PBS, pH7.4. | | Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. | | Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
| | Reference | 1.Review Cell Adh Migr.2012 Jul-Aug;6(4):374-84. Epub 2012 Jul 1.
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BackgroundL1 cell adhesion molecule (L1CAM), also known as CD171, is a cell adhesion receptor in the immunoglobulin superfamily, which plays an important role in the development of the nervous system. L1CAM interacts with a variety of ligands. Including axon protein 1, CD9, neurocan, and integrins. The molecule is a type I transmembrane (TM) protein that contains an 1101 aa extracellular region (aa 20-1120) plus a 114 aa cytoplasmic domain (aa 1144-1257). Recent work has identified L1CAM (CD171) as a novel marker for human carcinoma progression, and a candidate for anti-cancer therapy. bio-equip.cn AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
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