Fc γ RIIB/CD32b His Tag Protein, Human,specification,price,image-Bio-Equip in China

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Product Specification

Species	Human
Synonyms	Fc γ RIIb, CD32b;Fc gamma Receptor IIB/C, CD32, CD32b,CDw32
Accession	P31994-1
Amino Acid Sequence	Ala46-Pro217, with C-terminal His
Expression System	HEK293
Molecular Weight	27 -30 kDa(还原状态)
Purity	＞98%, by SDS-PAGE under reducing conditions
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	His Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, pH7.4
Reconstitution	Reconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.

Background

IgG Fc receptor (Fc γ R) is a member of the Ig superfamily, which plays a role in activating or inhibiting immune response. Human Fc γ Rs is identified as three types: RI (CD64), RII (CD32) and RIII (CD16). Human Fc γ RII / CD32 has three genes, CD32A, B and C, respectively. CD32 is a low affinity Fc receptor. Low-affinity immunoglobulin Fc γ region receptor II-b, namely CD32b, also known as FCGR2B, FCG2, IGFR2. CD32b was expressed on B cells and myeloid dendritic cells. The co-junction of CD32b on dendritic cells inhibits maturation and prevents cell activation. CD32b may also be a target for monoclonal antibody therapy of malignant tumors.