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ICAM-1/CD54 His Tag Protein, Mouse
ICAM-1/CD54 His Tag Protein, Mouse
Origin of place Singapore
Model UA010180-100μg
Supplier ANT BIO PTE.LTD.
Price 520
Hits 7
Updated 8/27/2025
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Product Specification


SpeciesMouse
SynonymsBB2, ICAM1, CD54, P3.58
AccessionP13597-1
Amino Acid SequenceGln28-Asn485, with C-8*His
Expression SystemHEK293
Molecular Weight72-95kDa
Purity>95% by SDS-PAGE
Endotoxin<0.1EU/μg
ConjugationUnconjugated
TagHis Tag
Physical AppearanceLyophilized Powder
Storage BufferPBS, pH7.4
ReconstitutionReconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1、Gu H F. et al. (2013) Association of intercellular adhesion molecule 1 (ICAM1) with diabetes and diabetic nephropathy. Front Endocrinol. 3: 179.

2、 Williams M R. et al. (2013) ICAM1 ligation‐induced transmigratory complex formation regulates leukocyte transendothelial migration. FASEB J. 27(S1): 57.5-57.5.

Background

ICAM-1 is a cell surface glycoprotein expressed at a low basal level in immune, endothelial (EC) and epithelial cells, but is up-regulated in response to inflammatory stimulation. The function of ICAM-1 has been best studied in leukocyte transendothelial migration (TEM), where ICAM-1 regulates leukocyte rolling and adhesive interactions with the vessel wall, and guides leukocyte crossing of the endothelial layer. More recently, functional studies identified several new roles of ICAM-1 in epithelial injury-resolution responses, innate and adaptive immune responses in inflammation, and tumorigenesis.
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