KGF/FGF-7 Protein, Mouse,specification,price,image-Bio-Equip in China

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Product Specification

Species	Mouse
Antigen	KGF/FGF-7
Synonyms	Heparin-binding growth factor 7 (HBGF-7), Keratinocyte growth factor (KGF)
Accession	P36363
Amino Acid Sequence	Cys32-Thr194
Expression System	E.coli
Molecular Weight	20kDa (Reducing)
Purity	＞95% by SDS-PAGE&HPLC
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, pH7.4
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1.MacDonald KP, Hill GR. Keratinocyte Growth Factor (KGF) in hematology and oncology. Curr Pharm Des. 2002;8(5):395-403. 2.Niu J, Chang Z, Peng B, Xia Q, Lu W, Huang P, Tsao MS, Chiao PJ. Keratinocyte growth factor/fibroblast growth factor-7-regulated cell migration and invasion through activation of NF-kappaB transcription factors. J Biol Chem. 2007 Mar 2;282(9):6001-11. Epub 2007 Jan 2.

Background

Keratinocyte growth factor (KGF), also known Fibroblast growth factor 7 (FGF-7) is a member of the fibroblast growth factor (FGF) family, and plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. KGF is also a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblast and endothelial cells. Studies of mouse and rat homologous protein implicated roles in morphogenesis of epithelium, re-epithelialization of wounds, hair development and early lung organogenesis.