VEGF-121 Protein, Human,specification,price,image-Bio-Equip in China

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Product Specification

Species	Human
Antigen	VEGF-121
Synonyms	Vascular Endothelial Growth Factor-A, VEGFA
Accession	P15692-9
Amino Acid Sequence	Ala27-Arg147
Expression System	E.coli
Molecular Weight	14kDa
Purity	＞95% by SDS-PAGE
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	20mM PB, 150mM NaCl, pH 7.4
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1.FASEB J. 2001 Jul;15(9):1667-9. 2.Cancer Gene Ther. 2016 May;23(5):125-32. Epub 2016 Apr 1.

Background

VEGF-121, an abundant splicing isoform of vascular endothelial growth factor (VEGF), exists as a disulfide-linked homodimer. It induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Contrast to other isoforms, VEGF-121 has very little affinity for heparin-sulfate proteoglycans, without recruiting Neuropilin1-expressing monocytes (NEMs), conferring to VEGF-121 the ability to diffuse freely, and increase tumor growth rate in vivo.