Adrenomedullin/ADM Fc Chimera Protein, Human,specification,price,image-Bio-Equip in China

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Product Specification

Species	Human
Synonyms	AM Protein, Human; PAMP Protein, Human
Accession	P35318
Amino Acid Sequence	Tyr95-Tyr146, with N-hIgG1 Fc
Expression System	HEK293
Molecular Weight	30-38kDa (Reducing)
Purity	＞95% by SDS-PAGE
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	Human Fc Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, pH7.4.
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1.Review Pol J Pharmacol . 2004 Jan-Feb;56(1):5-27.

Background

Adrenomedullin (ADM) is a 52-amino acid peptide homologous to calcitonin gene-related peptide (CGRP), a member of the adrenomedullin family originally isolated from human pheochromocytoma. It plays a key role in the regulation of many physiological processes, especially those of the cardiovascular and lymphatic systems. It also can be detected in lung, ventricle and kidney tissues. ADM is expressed in a variety of tissues in the human body and is fundamentally involved in multitude biological processes. It is believed that adrenomedullin functions through combinations of the calcitonin receptor like receptor and receptor activity-modifying proteins complexes, as well as CGRP receptors.