CD97/AGRE5 His Tag Protein, Human,specification,price,image-Bio-Equip in China

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Product Specification

Species	Human
Synonyms	CD97 Protein, Human; TM7LN1 Protein, Human
Accession	P48960-2
Amino Acid Sequence	Gln21-Gln398, with C-10*His
Expression System	HEK293
Molecular Weight	50-72kDa (Reducing)
Purity	＞95% by SDS-PAGE
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	His Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, pH7.4.
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1.nature scientific reports articles article Article Open access Published: 06 February 2019.

Background

CD97 is a member of the g protein-coupled receptor epidermal growth factor-7 transmembrane (EGF-TM7) subfamily and is involved in tumor cell adhesion, migration, angiogenesis, and apoptosis. CD97 is a receptor predominantly expressed in leukocytes and belongs to a new group of seven-span transmembrane molecules, which is also designed EGF-TM7 family. The family members are characterized by an extended extracellular region with several N-terminal epidermal growth factor-like domains two of which contain a calcium-binding site. Studies have shown that CD97 has been recognized as an effective target for the treatment of acute myeloid leukemia (AML) and glioblastoma.