FGF-basic(146aa) Protein, Human,specification,price,image-Bio-Equip in China

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Product Specification

Species	Human
Synonyms	bFGF,FGF-2;Heparin-binding growth factor 2;Basic fibroblast growth factor，FGFB,HBGF-2;FGF2; Fibroblast Growth Factor 2 (Basic)
Accession	P09038
Amino Acid Sequence	Pro143-Ser288
Expression System	E.coli
Molecular Weight	17 kDa (Reducing)
Purity	>95% by SDS-PAGE and HPLC.
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	20mM Tris, 500mM NaCl, pH8.0
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	·12 months from date of receipt, lyophilized powder stored at -20 to -80℃. ·3 months, -20 to -80℃ under sterile conditions after reconstitution. ·1 week, 2 to 8℃ under sterile conditions after reconstitution. ·Please avoid repeated freeze-thaw cycles.
Reference	1. J Biol Chem. 1996 Jun 21;271(25):15292-7. 2. Biosci Rep. 2017 Apr 10;37(2): BSR20170173.Print 2017 Apr 28. 3. Biochem Biophys Res Commun. 1986 Mar 13;135(2):541-8.

Background

Basic fibroblast growth factor (bFGF), also known as FGF2, is a member of the fibroblast growth factor (FGF) family. It is a highly specific chemotactic and mitogenic factor for many cell types, appears to be involved in remodeling damaged tissue, such as ulcer healing, vascular repair, traumatic brain injury (TBI). bFGF is a critical component of human embryonic stem cell culture medium. In addition, bFGF protein is a heparin-binding cationic protein involved in a variety of pathological conditions including angiogenesis and solid tumour growth. Thus, bFGF is regarded as a target for cancers chemopreventive and therapeutic strategies.