Biotinylated CDH17/LI-cadherin His&Avi Tag Protein, Human,specification,price,image-Bio-Equip in China

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Product Specification

Species	Human
Synonyms	Cadherin-17, HPT-1
Accession	Q12864
Amino Acid Sequence	Gln23-Met787, with C-10*His and Avi tag
Expression System	HEK293
Molecular Weight	95-100kDa (Reducing)
Purity	＞95% by SDS-PAGE
Endotoxin	<0.1EU/μg
Conjugation	Biotin
Tag	Avi Tag, His Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, pH7.4.
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1. Chen R ,Cao J ,Chen J , et al.Single nucleotide polymorphisms in the CDH17 gene of colorectal carcinoma[J].World Journal of Gastroenterology,2012,18(48):7251-7261. 2. 2. Long Z ,Zhou M ,Fu J , et al.Association between cadherin-17 expression and pathological characteristics of gastric cancer:A meta-analysis[J].World Journal of Gastroenterology,2015,21(12):3694-3705.

Background

Cadherin-17 or LI-cadherin is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins.Cadherin-17/LI-cadherin is a cadherin-like protein consisting of an extracellular region,7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. Cadherins preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. It's also involved in intestinal peptide transport.