IL-6 Protein, Mouse,specification,price,image-Bio-Equip in China

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Product Specification

Species	Mouse
Synonyms	Interleukin-6蛋白, IL-6蛋白;Interleukin-6, IL-6, B-Cell Hybridoma Growth Factor, Interleukin HP-1, Il6, Il-6
Accession	P08505
Amino Acid Sequence	Phe25-Thr211
Expression System	E.coli
Molecular Weight	22kDa
Purity	＞95% by SDS-PAGE&RP-HPLC
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	No Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	1x PBS, pH 7.4
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1. Cold Spring Harb Perspect Biol. 2014 Sep 4;6(10):a016295. 2. Cold Spring Harb Perspect Biol. 2018 Aug 1;10(8):a028456. 3. Biochem J. 2003 Aug 15;374(Pt 1):1-20.

Background

Interleukin 6 (IL-6) is a prototypical cytokine for maintaining homeostasis, Which promptly and transiently produced in response to infections and tissue injuries, contributes to host defense through the stimulation of acute phase responses, hematopoiesis, and immune reactions. When homeostasis is disrupted by infections or tissue injuries, IL-6 is produced immediately and contributes to host defense against such emergent stress through activation of acute-phase and immune responses. Dysregulation of IL-6-type cytokine signalling contributes to the onset and maintenance of several diseases, such as rheumatoid arthritis, inflammatory bowel disease, osteoporosis, multiple sclerosis and various types of cancer (e.g. multiple myeloma and prostate cancer).