Login    Join free Add to favorites    中文
Home >Products> Reagents >Other Reagents> 4-1BB/TNFRSF9 Fc Chimera Protein, Cynomolgus
4-1BB/TNFRSF9 Fc Chimera Protein, Cynomolgus
4-1BB/TNFRSF9 Fc Chimera Protein, Cynomolgus
Origin of place Singapore
Model UA010801-100μg
Supplier ANT BIO PTE.LTD.
Price 520
Hits 0
Updated 8/25/2025
  • Product Detail
  • Company Profile

Product Specification


SpeciesCynomolgus
SynonymsCDw137, ILA, TNFRSF9
AccessionA9YYE7
Amino Acid SequenceLeu24-Gln186, with C-terminal hIgG Fc
Expression SystemHEK293
Molecular Weight51-60kDa (Reducing)
Purity>95% by SDS-PAGE
Endotoxin<0.1EU/μg
ConjugationUnconjugated
TagHuman Fc Tag
Physical AppearanceLyophilized Powder
Storage BufferPBS, pH7.4.
ReconstitutionReconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

Melero I, et al. (2008) Multi-layered action mechanisms of CD137 (4-1BB)-targeted immunotherapies. Trends Pharmacol Sci. 29(8): 383-90. 2. Thum E, et al. (2009) CD137, implications in immunity and potential for therapy. Front Biosci. 14: 4173-88.

Background

CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 and CD137L are expressed in different human primary tumor tissues, suggesting that they may influence the progression of tumors. The best characterized activity of CD137 is its costimulatory activity for activated T cells.

bio-equip.cn
Request Infomation

* Name:
Title:
* Tel:
Fax:
* E-mail:
Postcode:
Institution/Company:
Address:
* Country:
Request infomation:
yes no
Request Quotation:
yes no
* Message:
Validated Code:
refresh
I agree to share my inquiry to the other matching suppliers.



Copyright(C) 2006-2025 Bio-Equip    E-mail:web@bio-equip.cn   沪ICP备06040519号