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NAP-2/CXCL7 Protein, Human
NAP-2/CXCL7 Protein, Human
Origin of place Singapore
Model UA040189-10μg
Supplier ANT BIO PTE.LTD.
Price 162
Hits 0
Updated 8/25/2025
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Product Specification


SpeciesHuman
SynonymsPPBP, B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL-7, LA-PF4, LDGF, MDGF, NAP2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1, pro-platelet basic protein
AccessionP02775
Amino Acid SequenceAla59-Asp128
Expression SystemE.coli
Molecular Weight9kDa (Reducing)
Purity

>95% by SDS-PAGE

Endotoxin<0.1EU/μg
ConjugationUnconjugated
TagNo Tag
Physical AppearanceLyophilized Powder
Storage Buffer20mM Tris, 300mM NaCl, pH8.0
ReconstitutionReconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

Wang YH, Shen CY, Lin SC, Kuo WH, Kuo YT, Hsu YL, Wang WC, Lin KT, Wang LH. Monocytes secrete CXCL7 to promote breast cancer progression. Cell Death Dis. 2021 Nov 17;12(12):1090. doi: 10.1038/s41419-021-04231-4. PMID: 34789744; PMCID: PMC8599470.

Background

Neutrophil Activating Peptide 2 (NAP-2), also known as CXCL7, is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. Recently, it has been shown that CXCL7 is secreted by tumor infiltrating monocytes, to stimulate cancer cell migration, invasion, and metastasis, contributing to the promotion of breast cancer progression. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity.

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