Product SpecificationSpecies | Human | Synonyms | PPBP, B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL-7, LA-PF4, LDGF, MDGF, NAP2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1, pro-platelet basic protein | Accession | P02775 | Amino Acid Sequence | Ala59-Asp128 | Expression System | E.coli | Molecular Weight | 9kDa (Reducing) | Purity | >95% by SDS-PAGE | Endotoxin | <0.1EU/μg | Conjugation | Unconjugated | Tag | No Tag | Physical Appearance | Lyophilized Powder | Storage Buffer | 20mM Tris, 300mM NaCl, pH8.0 | Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. | Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
| Reference |
Wang YH, Shen CY, Lin SC, Kuo WH, Kuo YT, Hsu
YL, Wang WC, Lin KT, Wang LH. Monocytes secrete CXCL7 to promote breast cancer
progression. Cell Death Dis. 2021 Nov 17;12(12):1090. doi:
10.1038/s41419-021-04231-4. PMID: 34789744; PMCID: PMC8599470.
|
BackgroundNeutrophil
Activating Peptide 2 (NAP-2), also known as CXCL7, is a platelet-derived
growth factor that belongs to the CXC chemokine family. This growth factor is
a potent chemoattractant and activator of neutrophils. Recently, it has been
shown that CXCL7 is secreted by tumor infiltrating monocytes, to stimulate
cancer cell migration, invasion, and metastasis, contributing to the
promotion of breast cancer progression. It also stimulates the formation and
secretion of plasminogen activator by synovial cells. The protein also is an
antimicrobial protein with bactericidal and antifungal activity.
bio-equip.cn
AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
|