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Human L1CAM/CD171 Protein, His tag
Human L1CAM/CD171 Protein, His tag
Origin of place Singapore
Model S0A5008-10μg
Supplier ANT BIO PTE.LTD.
Price 120
Hits 0
Updated 8/25/2025
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Product Specification


SpeciesHuman
SynonymsNeural cell adhesion molecule L1, N-CAM-L1, NCAM-L1, CAML1, MIC5
AccessionP32004
Amino Acid Sequence

Protein sequence (P32004, Ile20-Glu1120, with C-His tag) IQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATE

Expression SystemHEK293
Molecular WeightPredicted MW: 124.9 kDa Observed MW: 130, 180 kDa
Purity锛?5% by SDS-PAGE
Endotoxin<1EU/渭g
ConjugationUnconjugated
Tagwith C-His tag
Physical AppearanceLyophilized Powder
Storage Buffer

Lyophilized from a 0.2 渭m filtered solution of 0.2M PBS, pH7.4 with 3% trehalose.

ReconstitutionReconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 掳C as supplied.
6 months, -20 to -70 掳C under sterile conditions after reconstitution.
1 week, 2 to 8 掳C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.

Background

Neural cell adhesion molecule L1, also known as L1CAM, is a crucial glycoprotein in the nervous system. It belongs to the immunoglobulin superfamily of cell adhesion molecules. L1 plays a vital role in various neural processes, including neuronal migration, axonal outgrowth, and synapse formation. It mediates cell - cell adhesion through homophilic and heterophilic interactions, which are essential for the proper development and function of the nervous system. Mutations in the L1CAM gene can lead to several neurological disorders, such as X - linked hydrocephalus, mental retardation, and spastic paraplegia, highlighting its significance in maintaining normal neural function.

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