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Human IL-15 Protein, hFc tag
Human IL-15 Protein, hFc tag
Origin of place Singapore
Model S0A4044-25μg
Supplier ANT BIO PTE.LTD.
Price 225
Hits 0
Updated 8/25/2025
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Product Specification


SpeciesHuman
SynonymsInterleukin-15, IL15
AccessionP40933
Amino Acid Sequence

Protein sequence (P40933, Asn49-Ser162, with C-hFc tag) NWVNVISDLKKIEDLIQSMHIDATLYTESDVHPSCKVTAMKCFLLELQVISLESGDASIHDTVENLIILANNSLSSNGNVTESGCKECEELEEKNIKEFLQSFVHIVQMFINTS

Expression SystemHEK293
Molecular WeightPredicted MW: 38.8 kDa Observed MW: 45-60 kDa
Purity>95% by SDS-PAGE
Endotoxin<0.1EU/μg
ConjugationUnconjugated
Tagwith C-hFc tag
Physical AppearanceLyophilized Powder
Storage BufferLyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
ReconstitutionReconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage

12 months from date of receipt, -20 to -70 °C as supplied.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
1 week, 2 to 8 °C under sterile conditions after reconstitution.
Please avoid repeated freeze-thaw cycles.

Background

Interleukin-15 (IL-15) is a protein that in humans is encoded by the IL15 gene. IL-15 is an inflammatory cytokine with structural similarity to Interleukin-2 (IL-2). Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15 receptor beta chain (CD122) and the common gamma chain (gamma-C, CD132). IL-15 is secreted by mononuclear phagocytes (and some other cells) following infection by virus(es). This cytokine induces the proliferation of natural killer cells, i.e. cells of the innate immune system whose principal role is to kill virally infected cells. IL-15 is constitutively expressed by a large number of cell types and tissues, including monocytes, macrophages, dendritic cells (DC), keratinocytes, fibroblasts, myocyte and nerve cells. As a pleiotropic cytokine, it plays an important role in innate and adaptive immunity.

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