Human KIAA1522, His tag,specification,price,image-Bio-Equip in China

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Product Specification

Species	Human
Accession	Q9P206
Amino Acid Sequence	Protein sequence (Q9P206, Thr113-Asp201, with C-10*His) TSYVAESSTAEDALSIRSEMIQRKGSTFRPHDSFPKSGKSGRRRRERRSTVLGLPQHVQKELGLRNEREAPGTPRAPGARDAVRIPTVDGGGGSHHHHHHHHHH
Expression System	HEK293
Molecular Weight	Predicted MW: 11.6 kDa Observed MW: 10, 11, 18-25 kDa
Purity	＞95% by SDS-PAGE
Tag	with C-10*His
Physical Appearance	Lyophilized Powder
Storage Buffer	Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.
Reconstitution	Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.
Stability & Storage	12 months from date of receipt, -20 to -70 °C as supplied. 6 months, -20 to -70 °C under sterile conditions after reconstitution. 1 week, 2 to 8 °C under sterile conditions after reconstitution. Please avoid repeated freeze-thaw cycles.

Background

KIAA1522 was identified in 2000 by sequencing of human tissues. The KIAA1522 gene is localized on human chromosome 1p35.1 and contains 9 exons. In previous reports, KIAA1522 is demonstrated to be highly expressed in esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and breast cancer cell lines, and was related to tumor differentiation, invasion and metastasis. KIAA1522 expression was overexpressed in colorectal cancer and was positively correlated with poor prognosis of patients. However, its biological role and molecular mechanism in mediating tumor progression and distant metastasis have not yet been investigated.