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Cardiac Troponins I (cTnI) His Tag, Human
Cardiac Troponins I (cTnI) His Tag, Human
Origin of place Singapore
Model S0A9018-10μg
Supplier ANT BIO PTE.LTD.
Price 200
Hits 0
Updated 8/25/2025
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Product Specification


SpeciesHuman
Synonymscardiac troponin-I,Human Cardiac Troponin I;cardiac troponin-I,Human Cardiac Troponin I
AccessionP19429
Amino Acid SequenceMHHHHHHDDDDKADGSSDAAREPRPAPAPIRRRSSNYRAYATEPHAKKKSKISASRKLQLKTLLLQIAKQELEREAEERRGEKGRALSTRCQPLELAGLGFAELQDLCRQLHARVDKVDEERYDIEAKVTKNITEIADLTQKIFDLRGKFKRPTLRRVRISADAMMQALLGARAKESLDLRAHLKQVKKEDTEKENREVGDWRKNIDALSGMEGRKKKFES.
Expression SystemE.coli
Molecular Weight28 kDa
Purity>95%, by SDS-PAGE under reducing conditions
Endotoxin<1EU/μg
ConjugationUnconjugated
TagHis Tag
Physical AppearanceLyophilized Powder
Storage Buffer20mM Tris-HCl, 150mM NaCl, 1mM EDTA, 1mM DTT, 2M Urea, pH8.0
ReconstitutionReconstitute at less than 1 mg/mL according to the size in ultrapure water after rapid centrifugation .
Stability & Storage

· 12 months from date of receipt, -20 to -70 °C as supplied. 
· 6 months, -20 to -70 °C under sterile conditions after reconstitution.
· 1 week, 2 to 8 °C under sterile conditions after reconstitution.  
· Please avoid repeated freeze-thaw cycles.

Background

Cardiac Troponins I (cTnI), the Chinese name cardiac troponin I subunit, and cardiac troponin T subunit and cardiac troponin C subunit constitute cardiac troponin complex. Cardiac troponin complex is a calcium regulatory protein, which is used to regulate the contractile function of skeletal muscle and myocardium. When the concentration of intracellular Ca2+ is low, cTnI subunit can inhibit the interaction between troponin and troponin, and then inhibit the formation of myofibrinin. At present, cTnI is only found in cardiomyocytes and is released into the bloodstream after myocardial injury. Therefore, cTnI has high myocardial specificity and sensitivity, and is an important biomarker in the early diagnosis of acute myocardial infarction.

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