NBEAL1 (neurobeachin-like 1), also known as ALS2CR16 (amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) or ALS2CR17, is a 2,694 amino acid protein that belongs to the WD repeat Neurobeachin family. While highly expressed in kidney, brain, prostate and testis, NBEAL1 is also found at low levels in peripheral blood leukocytes, small intestine, ovary and colon. NBEAL1 contains one BEACH domain and two WD repeats, and undergoes alternative splicing to produce two isoforms. NBEAL2 (neurobeachin-like protein 2), also known as GPS or BDPLT4, is a 2,754 amino acid protein that belongs to the WD repeat neurobeachin family. Existing as four alternatively spliced isoforms, NBEAL2 contains one BEACH domain and five WD repeats. NBEAL2 is thought to play a role in α-granule biogenesis in megakaryocytes and is encoded by a gene that maps to human chromosome 3p21.31.

NBEAL1 Polyclonal Antibody detects endogenous levels of NBEAL1 protein.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:10000. Not yet tested in other applications.

NBEAL1 Polyclonal Antibody product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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